The copolymers are readily soluble in common organic solvents
such as chloroform, THF, and DMF. Thermal analysis revealed that the copolymers had good thermal stability. The fluorescence quenching behaviors of the hyperbranched copolymers by metal ions were studied. It was found that the fluorescence selleck products of the copolymers can be effectively quenched by Pd(2+). Moreover, the two hyperbranched copolymers exhibited different quenching efficiency, which may be related to difference in the hindrance for the chelation of pyridine unit with metal ions of the two polymers. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 121: 217-225, 2011″
“Previous reports have suggested an increased risk of psoriasis in MS patients. Worsening of dermatologic lesions during interferon therapy has been rarely reported, but activation of psoriatic arthritis has not been described until
now. The following is a case report. A 37-year-old woman affected by relapsing-remitting multiple sclerosis had severe worsening of cutaneous psoriasis and activation of psoriatic arthritis during interferon beta treatment. The symptoms resolved after therapy discontinuation. This case further supports that activation of psoriasis might be a rare side effect of IFNB therapy and suggests AZD2014 careful evaluation of concomitant morbidity to allow a patient-oriented treatment strategy.”
“The aim of this study was to determine the frequency of thyroid
autoimmunity in second grade primary school students and to examine the relationship between iodine and Hashimoto thyroiditis (HT). This was a cohort study performed with 1000 students. Urinary iodine levels, antithyroid peroxidase (anti-TPO) and antithyroglobulin (anti-Tg) antibodies were determined in all children. Children with anti-TPO Proteasome inhibitor or anti-Tg antibody positivity or with goiter were summoned for detailed examinations. In total, 36 cases (3.6%) were diagnosed as HT. The goiter frequency was found in 17.5% of the whole cohort. Additionally, iodine deficiency was found in 64.2% of all children. The median urinary iodine excretion was determined as 132 mu g/L (range 382 mu g/L) in the HT group, whereas it was 73 mu g/L (range 390 mu g/L) in children with goiter but without HT and 81 mu g/L (range 394 mu g/L) in normal children. The urinary iodine level of HT cases was significantly higher than the other two groups (p < 0.001). HT was also determined in 2% of patients with low urinary iodine levels, in 6.2% of patients with normal urinary iodine levels, and in 7.5% of patients with high urinary iodine levels. Our data demonstrates the close relationship between excessive iodine levels and autoimmunity.