During the following 30 years, his institute developed to become

During the following 30 years, his institute developed to become a widely recognized center of photosynthesis research and bioenergetics. Sapanisertib Numerous scientists from all over the world came as guest speakers, guest professors and postdocs. Among his assistants were Peter Böger, Günter Hauska, Wolfgang Haehnel, Richard Berzborn, Walter Oettmeier, Jens-Dirk Schwenn, Günter Wildner and Udo Johanningmeier. They are university professors spread over the whole country—some of them already retired. The number of capable scientists brought forth by Achim Trebst, is really amazing. A position

of associate professor was under the responsibility of Achim’s chair, too. He hired Rudolf Thauer, a capable young microbiologist working on bioenergetics; after a few years, Thauer ��-Nicotinamide concentration became a professor in Marburg and

Head of the Max-Planck-Institute for Terrestrial Microbiology in the same town. His successor in Bochum was the microbiologist Karl-Heinz Altendorf. For him this position was a “spring board” to become the Head of Microbiology at the University of Osnabrück. Already in the early 1960s, Achim was in contact with scientists working in the chemical industry, particularly in the Bayer company. A group of excellent chemists, among them Karl-Heinz Büchel and Wilfried Draber, had established a division of herbicide research in the Bayer company in Wuppertal. The photosynthetic apparatus was considered to be the most promising target of herbicides. Achim Trebst, as the German expert in the field of photosynthesis, S3I-201 nmr was the ideal partner of the industry chemists. A long lasting fruitful collaboration began between them. Careful structure-function relationship analyses on the one hand gave important

hints for new syntheses to the chemists, and on the other hand, several new inhibitors of photosynthesis permitted Alectinib molecular weight new important insights into the mechanism of photosynthesis. For photosynthesis research, the most successful compound (which never became a commercial herbicide) was the benzoquinone derivative DBMIB (2,5-dibromo-3-methyl-6-isopropyl-p-benoquinone = dibromothymoquinone). It may not be much of an exaggeration to state that some time or other every photosynthesis researcher must have employed it. DBMIB was a new type of inhibitor, inhibiting photosynthetic electron transport at the oxidizing side of plastoquinone. By means of this inhibitor a series of unsolved questions of the mechanism of electron transport between the two photosystems could be answered. The basic paper [A. Trebst, E. Hart and W. Draber (1970) On a new inhibitor of photosynthetic electron transport. Z. Naturforsch. 25b, 1157–1159] was cited innumerable times. In his research career, Achim returned to the quinones again and again. And he was right: quinones (ubiquinone, plastoquinone) are known to play a particularly important role in energy conservation since Peter Mitchell proposed the well-known chemiosmotic hypothesis.

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