Funding This work was supported by the UK Medical Research Counci

Funding This work was supported by the UK Medical Research Council [programme grant number U105960371]; MM Hamill was supported by a MRC PhD Clinical Research Training Fellowship. Conflicts of interest There were no conflicts of interest. Open Access This article is distributed under the terms of the Creative AZD6738 cell line Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. Electronic supplementary material Below is the link to the electronic supplementary material. ESM 1 DOCX 16 kb References 1. Brown Staurosporine research buy TT, McComsey GA (2006)

Osteopenia and osteoporosis in patients with HIV: a review of current concepts. Curr Infect Dis Rep 8(2):162–170PubMedCrossRef 2. Brown TT, Qaqish RB (2006) Antiretroviral therapy and the prevalence of osteopenia and osteoporosis: a meta-analytic review. AIDS 20(17):2165–2174PubMedCrossRef 3. Brown TT et al (2004) Reduced bone mineral

density in human immunodeficiency virus-infected patients and its association with increased central adiposity and postload hyperglycemia. J Clin Endocrinol Metab 89(3):1200–1206PubMedCrossRef 4. Welz T et al (2010) Efavirenz is associated with severe vitamin D deficiency and increased alkaline phosphatase. AIDS 24(12):1923–1928PubMedCrossRef 5. Bonjoch A et al (2010) High prevalence of and progression to low bone mineral density in HIV-infected patients: a longitudinal cohort study. AIDS 24(18):2827–2833PubMedCrossRef 6. Dolan SE, Kanter JR, Grinspoon S (2006) Longitudinal Selleckchem BAY 11-7082 analysis of bone density in human immunodeficiency virus-infected women. J Clin Endocrinol Metab 91(8):2938–2945PubMedCrossRef 7. Yin M et al (2005) Bone mass and mineral metabolism in HIV+ postmenopausal women. Osteoporos Int 16(11):1345–1352PubMedCrossRef 8. Arnsten JH et al (2006) HIV infection and bone mineral density 3-oxoacyl-(acyl-carrier-protein) reductase in middle-aged women. Clin Infect Dis 42(7):1014–1020PubMedCrossRef 9. Dolan SE et al (2004) Reduced bone density in HIV-infected women. AIDS 18(3):475–483PubMedCrossRef 10. Bolland MJ

et al (2007) Low body weight mediates the relationship between HIV infection and low bone mineral density: a meta-analysis. J Clin Endocrinol Metab 92(12):4522–4528PubMedCrossRef 11. Bolland MJ et al (2007) Bone mineral density remains stable in HAART-treated HIV-infected men over 2 years. Clin Endocrinol (Oxf) 67(2):270–275CrossRef 12. Republic of South Africa. Country progress report on the declaration of commitment on HIV/AIDS 2010. Report – reporting period: January 2008 – December 2009. http://​data.​unaids.​org/​pub/​report/​2010/​southafrica_​2010_​country_​progress_​report_​en.​pdf 13. Statistics South Africa (2010) Mid-year population estimates 2010: Pretoria South Africa. p. 1–16 14. Adams JS et al (2007) Vitamin D in defense of the human immune response. Ann N Y Acad Sci 1117:94–105PubMedCrossRef 15.

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